United Kingdom · Regional Lead · 2026-10-23
UK regulator authorizes oral treatment for plaque psoriasis
The once-daily medicine is approved for eligible adults and adolescents aged 12 and older after four Phase 3 trials.
The UK Medicines and Healthcare products Regulatory Agency authorized icotrokinra hydrochloride, marketed as Icotyde, on October 23. The approval covers moderate to severe plaque psoriasis in adults and adolescents aged 12 or older who weigh at least 40 kilograms and are candidates for systemic treatment.
The medicine is a 200-milligram tablet taken once a day. It selectively binds to and blocks the interleukin-23 receptor, part of an inflammatory pathway associated with immune-mediated conditions. Plaque psoriasis can produce scaly, itchy or painful skin patches and can also affect the nails.
MHRA says the authorization was supported by four Phase 3 studies involving 2,500 participants, including 72 adolescents. Each study showed efficacy at week 16 compared with placebo in the populations examined. The release does not provide a direct comparison with every other available systemic treatment.
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Technology · 2026-10-23
European study proposes three-stage response to hybrid threats
The research links early preparation, active defence and coordinated deterrence across cyber, information and physical domains.
The European Commission’s Joint Research Centre published a proposed strategy for countering hybrid threats on October 23. Developed with the European Centre of Excellence for Countering Hybrid Threats, the study addresses operations that combine tools such as cyberattacks, disinformation, unmanned vehicles and pressure on public institutions.
Its framework has three stages: proactive anticipation, active defence and reactive deterrence. The first emphasizes preparation and resilience in government, civic life and essential services. The second focuses on detecting an operation, identifying responsible actors and understanding the wider campaign behind individual events.
Read articleBusiness · 2026-10-22
Canada and EU ministers use Dublin talks to prepare next trade summit
The meetings mark ten years since CETA was signed and turn to digital trade, supply chains and economic security before an October 29–30 summit.
Canada’s international trade minister met European counterparts in Dublin on October 22, ten years after Canada and the European Union signed their Comprehensive Economic and Trade Agreement. The meetings are intended to prepare work for the Canada–EU summit scheduled in Montreal on October 29 and 30.
Global Affairs Canada says two-way trade in goods and services reached about C$178.3 billion in 2025. It reports that merchandise trade has grown by more than 78 percent from pre-CETA levels and that Canadian merchandise exports to the EU rose almost 21 percent from January through August 2026. Those figures are government comparisons, not a measure of the agreement’s effect in isolation.
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